The course was created within the framework of a grant for "Creation of online courses on health and medical sciences" (LOT number 3: Code: 2020-11-MP-0001/3; project "Providing by 2024 at least 20 percent of students in educational programs of higher education the opportunities to master individual courses, disciplines (modules), including in the format of online courses, using the resources of other organizations engaged in educational activities, including universities, ensuring that the quality of training of students is consistent with the world level").

DEAR LISTENERS! 

You start studying the course "Physical and chemical properties of proteins and its significance in medical and pharmaceutical practice". To successfully complete the course, you should study the materials on all topics, complete practical tasks after the modules, and pass intermediate tests. The maximum number of points per course is 100. For intermediate tests, a maximum of 25 points is obtained, and for a practical task - 20 points. The final test is 30 points. You have 60 minutes and 2 attempts to complete the task.

Course summary

The course provides students with knowledge about the structure, properties, functions, methods of studying proteins and its medical and pharmaceutical significance. It helps the students to be ready to use their knowledge in the study of clinical disciplines and in their future professional practice.

Course format

The course consists of: 

– video lectures that present the content of the topic;

– lecture notes in text format;

– materials for the practical lesson: test and practical tasks.

Each topic is completed with test and practical tasks (in text format). The final test of knowledge (credit) is carried out in the form of a test.

Requirements

To study this course, you should complete a basic course in chemistry, chemistry of organic polymers and their structural components, physical and colloid chemistry, Latin language and basic terminology, theoretical foundations of medicine, and normal physiology.

Course contents

Module 1. Classification, nomenclature, physical and chemical properties of amino acids and its significance for medical and pharmaceutical practice

1.1 Structure, classification, physical and chemical properties of amino acids

1.2. Medical and biological significance of α-amino acids. Medicinal products - amino acid derivatives

Module 2. Structure, physical and chemical properties of proteins. Physical and chemical methods of protein isolation and purification and its significance for medicine

2.1. Levels of protein structural organization. The change protein composition of the living organism in the ontogenesis and the diseases.

2.2. Physical and chemical properties of proteins. The precipitation of proteins from solution and its application in medicine

2.3. Methods for purification and separation of proteins and their importance in the diagnosis of various diseases

2.4. Protein fractions of blood serum and their importance in the diagnosis of various diseases

Competences

31.05.01 General medicine:

GPC-7 readiness for the use of basic physico-chemical, mathematical and other natural science concepts and methods in solving professional problems 

31.05.02 Pediatrics:

GPC-7 readiness for the use of basic physico-chemical, mathematical and other natural science concepts and methods in solving professional problems 

31.05.03 Dentistry:

GPC-7 readiness for the use of basic physico-chemical, mathematical and other natural science concepts and methods in solving professional problems 

33.05.01 Pharmacy:

GPC-1 is able to use basic biological, physico-chemical, mathematical methods for the development, research, and examination of medicinal products, and the manufacture of medicinal products. 

31.08.12 Functional diagnostics (the level of training of senior scholars):

PC–1 readiness to implement a set of measures aimed at preserving and promotion health and including the formation of a healthy lifestyle, prevention of the occurrence and (or) spread of diseases, its early diagnosis, identification of the causes and conditions of its occurrence and development, as well as aimed at eliminating the harmful effects of environmental factors on human health.

Directions

31.05.01 General medicine

31.05.02 Pediatrics

31.05.03 Dentistry

33.05.01 Pharmacy

06.03.01 Biology (Biochemistry profile)

Course length: 6 Course start date: 06.09.2021 Grade units: 1 Education hours: 36

Self enrolment (Student)

Course teachers

Elena V. Gromova

Dr. Sci. (Biology), Professor, Department of Biological and Pharmaceutical Chemistry with the course of organization and management of pharmacy

Lyudmila Ya. Labzina

Ph.D (Biology), Professor, Department of Biological and Pharmaceutical Chemistry with the course of organization and management of pharmacy

Elena N. Kovalenko

Ph.D. (Biology), Associate Professor, Department of Biological and Pharmaceutical Chemistry with the course of organization and management of pharmacy

Elena A. Alyamkina

Ph.D. (Chemistry), Associate Professor, Department of Biological and Pharmaceutical Chemistry with the course of organization and management of pharmacy

Ella V. Romanova

Ph.D. (Chemistry), Associate Professor, Department of Biological and Pharmaceutical Chemistry with the course of organization and management of pharmacy

Irina V. Abrashina

Ph.D. (Chemistry), Associate Professor, Department of Biological and Pharmaceutical Chemistry with the course of organization and management of pharmacy

Lyudmila V. Zotova

Ph.D. (Biology), Associate professor, Department of Biological and Pharmaceutical Chemistry with the course of organization and management of pharmacy

Albina V. Utkina

Head of the Volga region "Apteka Service Plus LLC"